Senior Scientist, Biochemistry - Targeted Protein Degradation (Highland Park)

AbbVie in Highland Park, IL

  • Industry: Scientific Research - Biology/Bioengineering
  • Type: Full Time
  • $100,225.00 - 162,670.00
position filled
We are seeking a highly-motivated biochemist, preferably with pharma/biotech experience, to join the Protein Degradation group in North Chicago, IL. This individual should have expertise in ubiquitin-related signaling or targeted protein degradation biology. A proven track record in successfully developing biochemical assays that probe this system is preferred. This individual should enjoy working with innovative technologies in a fast-paced environment.

Key responsibilities
  • Providing expertise in ubiquitin-related signaling and E3 ligase biology
  • Develop innovative strategies to study Protein Degrader engagement with the ubiquitin proteasome system
  • Developed robust in vitro profiling assays that support chemistry efforts in understanding structure-activity relationships
  • Apply novel techniques towards Protein Degrader drug discovery and elucidation of mechanism of action
  • Lead and interact with cross-functional scientific teams
  • Read and apply relevant scientific literature
  • Present research activities at internal and external meetings.

  • BS, MS, or PhD with 10+ (BS), 8+(MS), or 0+(PhD) in biochemistry, enzymology, chemical biology or related fields
  • Experience and publication track record in ubiquitin-proteasome system and/or targeted protein degradation biology
  • Proficient at developing enzyme activity assays and/or protein-protein interaction assays
  • Experience with molecular and cell biology techniques.
  • Experience analyzing data using statistical software programs such as GraphPad PRISM, Microsoft Excel, and Spotfire
  • Motivated, independent, and productive problem solver with a proven ability to advance new scientific understandings
  • Excellent verbal and non-verbal communication skills
  • Ability to work independently, yet works efficiently in teams to achieve objectives
  • Present research activities/results at internal and external meetings, and publish in peer-reviewed journals

Associated topics: aseptic, bio, bioinformatics, biology, biostatistics, microbiology, physical, stem cell, toxicologist, virus

You may be interested in these similar jobs!
Sr. Purification Scientist - RPA Enzymes
Astrix Technology Group in North Chicago, IL

Purification Scientist RPA Enzyme Project Position : Senior Scientist in the Biologics Process Design Purification group; primary function of this po…

Read More
CRA (Chicago)
Resourcing Life Science in Chicago, IL

Our Client is a Global pharma delivering treatements in a variety of therapeutic areas. They are currently seeking a CRA home based in Illinois Sk…

Read More
Radiation Therapist, 40hrs, Day, Evanston Hospital
Northshore University Hospital in Evanston, IL

NorthShore University HealthSystem (NorthShore) is a premier integrated healthcare delivery system consistently ranked as a Top 15 Teaching Hospital …

Read More
Highland Park Exam FM - Financial Mathematics Jobs
Varsity Tutors in Highland Park, IL

#Highland Park Exam FM - Financial Mathematics Tutor Jobs Varsity Tutors has students in #Highland Park looking for Exam FM - Financial Mathematics e…

Read More
2020 Experiential Internship (Graduate) - Oncology Discovery Scientist (West Chicago)
AbbVie in West Chicago, IL

As an AbbVie Experiential Intern, you'll participate in a paid, ten to twelve-week summer program that is focused on providing students with robust p…

Read More
Principal Research Scientist I, Chemistry (Elmwood Park)
AbbVie in Elmwood Park, IL

Key Responsibilities: Drive medicinal chemistry for assigned projects and ensure the delivery of high quality tools, leads and candidate molecules …

Read More
School Psychologist
Soliant Health in Highland Park, IL

School Psychologist Job (Full Time) near Highland Park, IL Soliant is partnering with a school near Highland Park, IL who is now looking to hire a…

Read More
Senior Scientist II/Principal Scientist I, Process Engineering Sciences (Glendale Heights)
AbbVie in Glendale Heights, IL

The Development Sciences Drug Product Development (DevSciDPD) organization within AbbVie develops and characterizes drug productformulations, combin…

Read More
Manager, Delivery Solution Clinical & Submission Support (Barrington)
AbbVie in Barrington, IL

AbbVie is looking for an engineer to join their Combination Product Development (CPD) team to lead the efforts in supporting design validation, clini…

Read More
Full Time::::Senior Data Engineer. (Streamwood)
RedLeo Software in Streamwood, IL

Senior Data Engineer. Full Time Only Oak Brook, IL. In short our client is looking to add a data engineer to their existing team. Role would focu…

Read More